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To evaluate the efficacy and safety of mini percutaneous nephro-lithotripsy (mini PCNL) and retrograde intrarenal surgery (RIRS) in treatment of renal stones larger than 20mm in its longest diameter. Patients & Methods: In a prospective randomized study including 40 patients divided into two groups each 20 patient. Gathering An included 12 guys and 8 females with age went from 15 to 62 years had smaller than expected PCNL for renal pelvic and calyceal stones. Gathering B included 8 guys and 12 females with age extended from 18 to 65 years of age had RIRS. Adaptable ureteroscopy was utilized for pelvic and calyceal stones utilizing holmium:YAG laser (tidying approach). In the two gatherings the strategy result regarding Operative time, Blood misfortune, clinic remain, entanglements utilizing changed Clavien reviewing framework , the need of assistant systems , stone free rates following 3 weeks by utilizing CTUT, were assessed measurably. Measurable investigation of the information indicated that there was immaterial contrast between the {mean ± SD} of the BMI in patients of gathering A which was {27.850±3.183} kg/m2; while in patients of gathering B was {29.700±7.927} kg/m2 . With respect to measure, there was immaterial contrast between the {mean ± SD} of gathering A which was 2.57±0.22mm, while in bunch B was 2.6±0.24mm. With respect to usable time the {mean ± SD} of gathering A was 104.43±14.79 minutes which was altogether (P<0.05) higher contrasted with bunch B 59.71±19.44 minutes. As with respect to emergency clinic stay it was unimportantly (P lower 0.05) higher in bunch A 1.41±0.46 days contrasted with bunch B 1.29±0.44 days. Concerning free rate 89 % of patients rewarded with bunch A were without stone (17 out of 20), while in bunch B 83.4% of patients were sans stone (16 out of 20) following 3 weeks by utilizing CTUT imaging. As to utilizing changed Clavien evaluating correlation with our investigation in which Grade 1: 1 in bunch An and 0 in bunch B , grade 2: 1 in bunch An and 0 in bunch B , grade 3A : 1 in bunch An and 0 in bunch B likewise grade 3B : 0 in bunch An and 0 in bunch B additionally 0 in grade 4 and 5 in the two gatherings In patients with renal stones bigger than 20 mm , results indicated that little PNCL has higher stone free rate and longer employable time than RIRS in cost of higher entanglements rate, blood misfortune, and longer medical clinic remain.

Key words

MPCNL, RIRS.