Effect of Conventional Phototherapy on Platelet Count in Full Term and Preterm Neonates with Indirect Hyperbilirubinemia

A.A.Abou Amer1 , A.E.Diab1, O.S.El-Shimi2 and M.M.Abd El-Hamied1"


Phototherapy plays a significant role in prevention and treatment of hyperbilirubinemia. Side effect of phototherapy on platelet count has not been described in detail. A few creators watched diminished platelet includes in neonates presented to photograph treatment. Our plan to assess the impact of ordinary phototherapy on platelet include in neonates with roundabout hyperbilirubinemia in benha college medical clinic. This examination comprised of 100 back to back neonates with hyperbilirubinemia both preterm and full term included conceded in neonatal emergency unit phototherapy, in the age gathering of 2 days to 28 days with negative direct Coomb's test and negative C - responsive protein., Serum bilirubin and CBC with Platelet tally was performed before beginning PT, Twenty four hours (24Hrs) after PT and forty eight hours (48 Hrs) after phototherapy or at stopping of phototherapy whichever was before. Information examination was performed utilizing the product SPSS (Statistical Package for the Social Sciences) variant 20. The aftereffects of this examination demonstrated A sum of 100 (100%) neonates with roundabout hyperbilirubinemia were tried out the investigation, of which 52(52 %) were male and 48(48%) were female. 62(62 %) were Full term 38(38 %) were preterm. Platelet include in preterm and full term neonates was fundamentally diminished after 24 h and 48 h of beginning phototherapy when contrasted and platelet depend on affirmation (P= 0.001 each) . At the point when whole examination populace was concentrated in general, it was discovered that Platelet tally was fundamentally diminished after 24 hrs and 48 hrs of beginning phototherapy when contrasted and platelet depend on affirmation (P <0.001 each) , and platelet tally at 24 h subsequent to beginning phototherapy was essentially diminished than 48 h in the wake of beginning phototherapy (P <0.001).In end; phototherapy in infants with circuitous hyperbilirubinemia prompts decline in platelet include both in full term and preterm babies. The diminishing in platelet tally after phototherapy is transient. This lessening in platelet check is progressively huge following 24 hours of phototherapy.

Key words

Phototherapy, Hyperbilirubinemia, Platelet count.