Hyper Triglyceridemia Induced Pancreatitis in Children with Diabetic Ketoacidosis

B.M.Hassanein1, H.R.Omar1, W.A.Abdelhaleem2, and A.M. Moussa1"


Diabetic ketoacidosis (DKA) is one of the most serious complications of diabetes. In DKA, the deficiency of insulin activates lipolysis in adipose tissue releasing increased free fatty acid (FFA) , which accelerates formation of very low density lipoprotein (VLDL) in the liver. In extreme hypertriglyceridemia, there is an expanded danger of creating intense pancreatitis. This investigation expected to assess the serum level of triglycerides and serum level of lipase as serological markers for intense pancreatitis in kids with Diabetic Ketoacidosis (DKA). For this situation controlled investigation, subjects were arranged into 2 gatherings; quiet gathering: Included 50 sort 1 diabetic youngsters, Control gathering: included 30 clearly solid kids age and sexual orientation coordinated to Diabetic patients gathering. The current examination was directed on 50 youngsters with DKA. Their mean age was 6.4 years, they were 24 guys (48%) and 26 females (52%). Notwithstanding 30 sound benchmark group of coordinated age and sexual orientation. DKA indicated altogether higher TC, LDL, fundamentally lower HDL when contrasted with control gathering. TG was fundamentally higher in DKA bunch when contrasted with control gathering. DKA with AP demonstrated fundamentally higher TC, LDL, and altogether lower HDL when contrasted with DKA without AP. TG and lipase levels were altogether higher in DKA with AP when contrasted with DKA without AP subgroups.

Key words

Hyper triglyceridemia, Pancreatitis, Diabetic Ketoacidosis.